Document Detail


Anti-acetylcholinesterase antibody in myasthenic syndrome.
MedLine Citation:
PMID:  9642328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the relationship between antibodies to acetylcholinesterase and myasthenic syndrome. METHODS: Serum class specific antibodies to acetylcholinesterase and acetylcholine receptor were prepared with solid phase enzyme-linked immunosorbent assay in 51 patients with myasthenic syndrome, 31 controls with other neurological diseases (diseased controls) and 44 normal controls. RESULTS: The positive rate of anti-acetylcholinesterase antibody in patients with myasthenic syndrome was 25%, while the results of the other two control groups were negative. Furthermore, the positive rate in patients without myasthenia gravis was 45%, which was much higher than that (13%) in those with myasthenic gravis. CONCLUSION: Anti-acetylcholinesterase antibody may play a role in the pathogenesis of myasthenic syndrome.
Authors:
J Tang; J Yuan; H Hao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical journal     Volume:  110     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1998-08-11     Completed Date:  1998-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  698-700     Citation Subset:  IM    
Affiliation:
Department of Neurology, First Affiliated Hospital of Beijing Medical University, China.
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MeSH Terms
Descriptor/Qualifier:
Acetylcholinesterase / immunology*
Adolescent
Adult
Autoantibodies / blood*
Child
Child, Preschool
Deglutition Disorders / immunology
Dyspnea / immunology
Female
Humans
Infant
Male
Muscle Weakness / immunology
Myasthenia Gravis / immunology*
Syndrome
Chemical
Reg. No./Substance:
0/Autoantibodies; EC 3.1.1.7/Acetylcholinesterase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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