Document Detail

Anti-Salmonella activity of CP-99,219, a novel azabicyclo-naphthridone fluoroquinolone.
MedLine Citation:
PMID:  8957578     Owner:  NLM     Status:  MEDLINE    
The antimicrobial activity of CP-99,219 was determined by the broth dilution method against 67 clinical isolates of Salmonella typhi. Ninety-one percent of the isolates were inhibited by < or = 0.12 mg/l of this quinolone, and all the 67 by 2.0 mg/l. Its inhibitory activity was slightly superior to ciprofloxacin and norfloxacin and significantly greater than ampicillin, augmentin, chloramphenicol and trimethoprim-sulphamethoxazole.
S M Qadri; B A Cunha; Y Ueno; E A Walters
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chemotherapy     Volume:  42     ISSN:  0009-3157     ISO Abbreviation:  Chemotherapy     Publication Date:    1996 Nov-Dec
Date Detail:
Created Date:  1997-06-09     Completed Date:  1997-06-09     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0144731     Medline TA:  Chemotherapy     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  439-42     Citation Subset:  IM    
King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
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MeSH Terms
Anti-Bacterial Agents / pharmacology*
Anti-Infective Agents / pharmacology*
Microbial Sensitivity Tests
Naphthyridines / pharmacology*
Salmonella typhi / drug effects*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Infective Agents; 0/Fluoroquinolones; 0/Naphthyridines; 146836-84-2/trovafloxacin

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