Document Detail

Anti-Ce complicating two consecutive pregnancies with increasing severity of haemolytic disease of the newborn.
MedLine Citation:
PMID:  12581455     Owner:  NLM     Status:  MEDLINE    
The Ce antigen is expressed on red cells of individuals with Rh haplotypes, R1 or CDe and r' or Cde. However, anti-Ce is rare, and only two cases of severe haemolytic disease of the newborn (HDN) caused by this antibody have been described (Malde et al., 2000; Wagner et al., 2000). We describe a woman who was found to have anti-Ce in her second pregnancy, resulting in a neonate with HDN that required exchange transfusion. She subsequently had a twin pregnancy, where both the twins were affected by severe haemolytic disease (HD) of the fetus because of anti-Ce and required repeated fetal transfusions, followed by exchange transfusions after birth. This is the first reported case of HD caused by anti-Ce requiring fetal transfusions.
E Ranasinghe; E Goodyear; G Burgess
Related Documents :
24575805 - Women's antenatal preferences for delivery route in a setting with high cesarean sectio...
7724145 - Intrauterine therapy for homozygous alpha-thalassemia.
2110805 - Rh haemolytic disease: continuing problem of management.
4016025 - Homozygous alpha-thalassaemia: clinical presentation, diagnosis and management. a revie...
7143475 - Fetal distribution of mercury following introduction of methylmercury into porcine mate...
3464145 - Influence of pregnancy on diabetic retinopathy.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Transfusion medicine (Oxford, England)     Volume:  13     ISSN:  0958-7578     ISO Abbreviation:  Transfus Med     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-02-12     Completed Date:  2003-10-20     Revised Date:  2008-07-31    
Medline Journal Info:
Nlm Unique ID:  9301182     Medline TA:  Transfus Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  53-5     Citation Subset:  IM    
Red Cell Immunohaematology Antenatal Service, National Blood Service, Cambridge, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Transfusion
Diseases in Twins
Erythroblastosis, Fetal / etiology,  immunology*,  therapy
Glycoproteins / analysis,  immunology*
Rh-Hr Blood-Group System / immunology*
Reg. No./Substance:
0/Glycoproteins; 0/RHCE protein, human; 0/Rh-Hr Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Alloimmune neonatal neutropenia linked to anti-HNA-4a.
Next Document:  Dieulafoy's lesion of duodenum: a case report.