| Anti-Ce complicating two consecutive pregnancies with increasing severity of haemolytic disease of the newborn. | |
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MedLine Citation:
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PMID: 12581455 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Ce antigen is expressed on red cells of individuals with Rh haplotypes, R1 or CDe and r' or Cde. However, anti-Ce is rare, and only two cases of severe haemolytic disease of the newborn (HDN) caused by this antibody have been described (Malde et al., 2000; Wagner et al., 2000). We describe a woman who was found to have anti-Ce in her second pregnancy, resulting in a neonate with HDN that required exchange transfusion. She subsequently had a twin pregnancy, where both the twins were affected by severe haemolytic disease (HD) of the fetus because of anti-Ce and required repeated fetal transfusions, followed by exchange transfusions after birth. This is the first reported case of HD caused by anti-Ce requiring fetal transfusions. |
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Authors:
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E Ranasinghe; E Goodyear; G Burgess |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Transfusion medicine (Oxford, England) Volume: 13 ISSN: 0958-7578 ISO Abbreviation: Transfus Med Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-02-12 Completed Date: 2003-10-20 Revised Date: 2008-07-31 |
Medline Journal Info:
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Nlm Unique ID: 9301182 Medline TA: Transfus Med Country: England |
Other Details:
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Languages: eng Pagination: 53-5 Citation Subset: IM |
Affiliation:
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Red Cell Immunohaematology Antenatal Service, National Blood Service, Cambridge, UK. edmund.ranasinghe@nbs.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Transfusion Diseases in Twins Erythroblastosis, Fetal / etiology, immunology*, therapy Female Glycoproteins / analysis, immunology* Humans Pregnancy Rh-Hr Blood-Group System / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Glycoproteins; 0/RHCE protein, human; 0/Rh-Hr Blood-Group System |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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