Document Detail


Anthropometric and intellectual evaluation of individuals with Prader-Willi syndrome.
MedLine Citation:
PMID:  17588847     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prader-Willi syndrome (PWS) is a rare, multifaceted genetic disorder resulting from the absence of normally active paternally expressed genes from the 15q11-q13 chromosome region. Due to a lack of anthropometric and intellectual data in Taiwan, we attempted these evaluations. Twenty patients (14 males/6 females) aged 7-23 years with molecularly confirmed PWS were enrolled with parental consent. Their mean height standard deviation score (SDS) was -1.26 +/- 1.89 (from -4.3 to +2.16); mean weight SDS was +1.77 +/- 2.00 (from -0.44 to +5.89); mean body mass index SDS was +3.84 +/- 10.54 (from -0.08 to +10.48); and mean body fat tissue SDS was 39.4 +/- 10.54% (14.7-57.8%) by an InBody 3.0 analyzer. All were hypogonadal. Nine of them had once been given growth hormone therapy, and were taller and slimmer than the rest. Their intelligence tests showed full intelligence quotient = 52.0 +/- 7.6; verbal intelligence quotient = 55.9 +/- 8.77; performance intelligence quotient = 53.2 +/- 9.0. Chronic health status revealed that diabetes was prevalent among the older population. Their IQ was in the range of those with moderate retardation.
Authors:
San-Ging Shu; Shu Chien; Yen-Ching Wu; Pei-Ling Tsai; Joung-Kun Yih
Related Documents :
2881647 - Rat corticotropin, insulin and thyroid hormone levels during the acute phase response t...
8971657 - Glucose modulates growth of gingival fibroblasts and periodontal ligament cells: correl...
11716617 - Diagnosis and management of diabetes mellitus in five cats with somatotrophic abnormali...
3530937 - Insulin-like growth factors/somatomedins: structure, secretion, biological actions and ...
16005097 - Comparisons of the outcomes on control, type of management and complications status in ...
9131677 - Assessment of perioperative glycerol metabolism by stable isotope tracer technique.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the Formosan Medical Association = Taiwan yi zhi     Volume:  106     ISSN:  0929-6646     ISO Abbreviation:  J. Formos. Med. Assoc.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-25     Completed Date:  2007-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214933     Medline TA:  J Formos Med Assoc     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  509-12     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Taichung Veterans General Hospital, and Chung-Shan Medical University, Taichung, Taiwan. ssgs@vghtc.gov.tw
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Body Size*
Child
Female
Humans
Intelligence*
Male
Prader-Willi Syndrome / pathology,  psychology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary effusion lymphoma involving both pleural and abdominal cavities in a patient with hepatitis ...
Next Document:  Constrained contraceptive choice: IUD prevalence in Uzbekistan.