Document Detail


Anthropometric correlates of lipoprotein profile and blood pressure in high BMI African American children.
MedLine Citation:
PMID:  20064141     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To explore the association of anthropometric indices with lipoprotein profile and blood pressure as risk factors of cardiovascular disease, in African American (AA) children. METHODS: A cross-sectional analysis was carried out on children aged 9-13 years with BMI >85th percentile. Height, weight, waist and hip circumferences, % body fat and blood pressure [systolic (sBP) and diastolic (dBP)] were measured. Fasting plasma levels of triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), intermediate density lipoprotein cholesterol (IDL-C) and very low-density lipoprotein cholesterol (VLDL-C) were analysed. RESULTS: After accounting for age, gender and pubertal status of the child, multiple linear regression models showed that waist circumference and BMIz were strong predictors for lipoprotein variables. In independent analysis, waist circumference and BMI z-scores were found to be interdependently associated with TG, LDL-C:HDL-C ratio, VLDL-C and sBPz. However, for HDL-C, TG:HDL-C ratio and dBPz, waist circumference was independently and more strongly associated with these risk factors than BMI. CONCLUSION: Waist circumference was a stronger predictor for lipoprotein variables and blood pressure in high BMI AA children than other anthropometric indices, and may be adequate as a screening test to identify children who are at increased risk for cardiovascular disease.
Authors:
A Raman; S Sharma; M D Fitch; S E Fleming
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-01-07
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-17     Completed Date:  2010-08-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  912-9     Citation Subset:  IM    
Affiliation:
The Robert C and Veronica Atkins Center for Weight and Health, University of California, Berkeley, CA, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
African Americans / statistics & numerical data*
Anthropometry
Blood Pressure / physiology*
Body Mass Index
Cardiovascular Diseases / ethnology*
Child
Cross-Sectional Studies
Female
Humans
Linear Models
Lipoproteins / blood*
Male
Obesity / blood,  ethnology*,  physiopathology
Risk Factors
Waist Circumference*
Chemical
Reg. No./Substance:
0/Lipoproteins

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