Document Detail


Anthropometric characteristics and success rates of oral or vaginal misoprostol for pregnancy termination in the first and second trimesters.
MedLine Citation:
PMID:  20206352     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the effect of anthropometric characteristics related to weight on medical pregnancy termination with misoprostol. METHODS: In this prospective cohort study, 454 women admitted for medical pregnancy termination in the first or second trimester took 400 microg of misoprostol sublingually plus 800 microg of misoprostol vaginally or orally. The regimen was readministered after 24 hours if there was no response or the abortion was incomplete, and surgical evacuation was done when needed. Linear regression was performed for possible correlations between the studied characteristics and treatment process and outcome. RESULTS: There was no correlation between the number of misoprostol administrations and any of the studied anthropometric characteristics. The numbers of both misoprostol administrations and surgical interventions were associated with oral administration. CONCLUSION: The route of misoprostol administration, but not anthropometric characteristics related to weight, were found to be associated with the success of pregnancy termination with misoprostol.
Authors:
Louis-Jacques van Bogaert; Asha Misra
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2010-03-04
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  109     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-07     Completed Date:  2010-08-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  213-5     Citation Subset:  IM    
Copyright Information:
Copyright 2010 International Federation of Gynecology and Obstetrics. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Saint Rita's Hospital, Glen Cowie, Limpopo Province, South Africa. ljfvanbo@lantic.net
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MeSH Terms
Descriptor/Qualifier:
Abortifacient Agents, Nonsteroidal / administration & dosage*
Abortion, Induced / methods*
Administration, Intravaginal
Administration, Oral
Administration, Sublingual
Adult
Anthropometry / methods
Body Weight
Cohort Studies
Female
Humans
Linear Models
Misoprostol / administration & dosage*
Pregnancy
Pregnancy Trimester, First
Pregnancy Trimester, Second
Prospective Studies
Young Adult
Chemical
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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