Document Detail


Anterior uveitis in a child with Takayasu's arteritis.
MedLine Citation:
PMID:  15180852     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Takayasu's arteritis is a rare idiopathic arteriopathy that produces narrowing and eventually closure of affected blood vessels. Ocular symptoms typically occur late in the disease process in those individuals who have severe involvement of the aortic arch and the carotid arteries. Visual loss typically occurs as a result of either systemic hypertension or concomitant ocular hypo-perfusion. We describe an unusual case of Takayasu's arteritis presenting in a child who complained of painful blurred vision. In this individual, no carotid artery disease was identified on vascular imaging and no evidence of impairment of ocular perfusion was demonstrable. Vision loss in this instance was due to anterior uveitis and cystoid maculopathy. These are atypical and rarely described features of Takayasu's arteritis. The patient responded well to anti-inflammatory treatment and his symptoms resolved. The clinical significance of these findings are discussed and the relevant literature reviewed.
Authors:
Mark A McDonald; Elvis Ojaimi; Ian Favilla
Publication Detail:
Type:  Case Reports; Letter    
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  32     ISSN:  1442-6404     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-07     Completed Date:  2004-07-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  336-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Child
Drug Therapy, Combination
Fluorescein Angiography
Glucocorticoids / therapeutic use
Humans
Immunosuppressive Agents / therapeutic use
Magnetic Resonance Angiography
Male
Methotrexate / therapeutic use
Prednisolone / therapeutic use
Takayasu Arteritis / complications*,  diagnosis,  drug therapy
Uveitis, Anterior / diagnosis,  drug therapy,  etiology*
Chemical
Reg. No./Substance:
0/Glucocorticoids; 0/Immunosuppressive Agents; 50-24-8/Prednisolone; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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