Document Detail

Anterior mediastinal metastasis of testicular germ cell tumor: relation to benign thymic hyperplasia.
MedLine Citation:
PMID:  9358229     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the anterior mediastinal mass in recurrent testicular cancer, with relation to thymic hyperplasia after treatment. METHODS: The anterior mediastinal regions were fully evaluated by chest computed tomography (CT) at the initial staging and after treatment in 24 of 44 patients with testicular cancer. RESULTS: One patient with stage IIB tumor had thymic hyperplasia before treatment, and one with stage III had benign thymic hyperplasia after chemotherapy with salvage surgery. Three of 4 patients who had recurrence had an anterior mediastinal mass. One had benign thymic hyperplasia confirmed by histology and 2 had metastatic tumor confirmed by histology and clinical course, in which the mass became so enlarged that it obstructed major vessels. CONCLUSION: Although the relationship of the CT finding to the response to treatment in the anterior mediastinal mass and other metastatic lesions provide some clues helpful in differentiating benign from malignant masses, surgical exploration is recommended for the patient with an indication for salvage surgery.
K Suzuki; K Kurokawa; T Suzuki; I Yoshida; A Otaki; K Imai; H Yamanaka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European urology     Volume:  32     ISSN:  0302-2838     ISO Abbreviation:  Eur. Urol.     Publication Date:  1997  
Date Detail:
Created Date:  1997-11-24     Completed Date:  1997-11-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7512719     Medline TA:  Eur Urol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  371-4     Citation Subset:  IM    
Department of Urology, Gunma University School of Medicine, Maebashi, Japan.
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MeSH Terms
Combined Modality Therapy
Germinoma / pathology,  radiography,  secondary*
Mediastinal Neoplasms / pathology,  radiography,  secondary*
Middle Aged
Salvage Therapy
Testicular Neoplasms / complications,  pathology*,  therapy
Thymus Hyperplasia / etiology*,  radiography
Tomography, X-Ray Computed

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