Document Detail

Anterior and intermediate uveitis cases referred to a tertiary centre in Alberta.
MedLine Citation:
PMID:  18033328     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We investigated the characteristics and causes of various uveitis subtypes in patients presenting to the Regional Eye Centre at the Royal Alexandra Hospital, University of Alberta, Edmonton, Alta., and estimated the incidence of anterior uveitis in northern Alberta. METHODS: A retrospective study was conducted of all patients presenting with uveitis to a single, full-time ophthalmologist at the Regional Eye Centre from September 2004 to June 2005. Uveitis was classified according to onset, severity, anatomical subtype, etiology, recurrence rate, and response to treatment. Statistical analysis was used to compare patients referred by ophthalmologists with those referred by non-ophthalmologists. RESULTS: Two hundred and nine eyes of 171 patients were included in the study. Ophthalmologist referrals consisted of 67.4% anterior, 14.0% intermediate, and 18.6% panuveitis, and non-ophthalmological referrals were 92.8% anterior, 5.4% intermediate, and 1.8% panuveitis. Referrals from ophthalmologists were significantly more likely to be chronic, recurrent, and (or) less responsive to treatment than referrals from other sources. INTERPRETATION: Referral bias strongly affects the proportions of uveitis subtypes seen. Human leukocyte antigen-B27-associated diseases (especially ankylosing spondylitis), sarcoidosis, and herpes infections should be considered among the most likely causes of uveitis to be diagnosed in this patient population.
Stanley M Chan; Matthew Hudson; Ezekiel Weis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  42     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-06     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  860-4     Citation Subset:  IM    
Department of Ophthalmology, Royal Alexandra Hospital, Vancouver, BC.
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MeSH Terms
Aged, 80 and over
Alberta / epidemiology
Child, Preschool
Herpesviridae Infections / complications
Hospitals, Special / statistics & numerical data
Hospitals, State
Middle Aged
Referral and Consultation / statistics & numerical data*
Retrospective Studies
Risk Factors
Sarcoidosis, Pulmonary / complications
Spondylitis, Ankylosing / complications
Uveitis, Anterior / classification,  epidemiology*,  etiology
Uveitis, Intermediate / classification,  epidemiology*,  etiology

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