| Anterior ST segment depression in acute inferior myocardial infarction as a marker of greater inferior, apical, and posterolateral damage. | |
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MedLine Citation:
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PMID: 3788768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical significance of anterior precordial ST segment depression during acute inferior myocardial infarction was evaluated in 67 consecutive patients early after onset of symptoms with gated blood pool scans, thallium-201 perfusion images, and 12-lead ECGs. Patients with anterior ST depression (n = 33) had depressed mean values for left ventricular ejection fraction (54 +/- 2% [mean +/- S.E.M.] vs 59 +/- 2%; p = 0.02), cardiac index (3.1 +/- 0.2 vs 3.6 +/- 0.2 L/m2; p = 0.03), and ratio of systolic blood pressure to end-systolic volume (2.0 +/- 0.1 vs 2.5 +/- 0.3 mm Hg/ml; p = 0.04) compared to patients with no anterior ST depression (n = 34). Patients with anterior ST depression had (1) lower mean wall motion values for the inferior, apical, and inferior posterolateral segments (p less than 0.05) and (2) greater reductions in thallium-201 uptake in the inferior and posterolateral regions (p less than 0.05). However, anterior and septal (1) wall motion and (2) thallium-201 uptake were similar in patients with and without ST depression. Thus, anterior precordial ST segment depression in patients with acute inferior wall myocardial infarction represents more than a reciprocal electrical phenomenon. It identifies patients with more severe wall motion impairment and greater hypoperfusion of the inferior and adjacent segments. The poorer global left ventricular function in these patients is a result of more extensive inferior infarction and not of remote septal or anterior injury. |
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Authors:
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T D Ruddy; T Yasuda; H K Gold; R C Leinbach; J B Newell; K A McKusick; C A Boucher; H W Strauss |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American heart journal Volume: 112 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1986-12-30 Completed Date: 1986-12-30 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1210-6 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Electrocardiography* Heart Ventricles / physiopathology, radionuclide imaging Humans Myocardial Infarction / diagnosis*, physiopathology Prospective Studies Radioisotopes / diagnostic use Stroke Volume Systole Thallium / diagnostic use Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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HL07416/HL/NHLBI NIH HHS; HV7-2940/HV/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Radioisotopes; 7440-28-0/Thallium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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