Document Detail

Antenatal exposure to magnesium sulfate and neuroprotection in preterm infants.
MedLine Citation:
PMID:  21575805     Owner:  NLM     Status:  In-Data-Review    
Cerebral palsy is a leading cause of childhood neuromotor disability and is strongly associated with preterm delivery. Basic science research and some observational studies have suggested a neuroprotective benefit from antenatal exposure to magnesium sulfate. Recent randomized controlled studies and meta-analyses suggest that antenatal exposure to magnesium sulfate before anticipated preterm birth is associated with reduction in the risk of developing cerebral palsy or its associated neurologic disabilities in surviving infants. More importantly. this benefit has been achieved without increasing the risk of perinatal mortality.
Maged M Costantine; Nathan Drever
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology clinics of North America     Volume:  38     ISSN:  1558-0474     ISO Abbreviation:  Obstet. Gynecol. Clin. North Am.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709551     Medline TA:  Obstet Gynecol Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351-66     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0587, USA.
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