Document Detail

Antenatal diagnosis of fetal hepatic hemangioma treated with maternal corticosteroids.
MedLine Citation:
PMID:  10546738     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Infantile hepatic hemangioma is a benign liver tumor with potentially fatal complications. Response of these lesions to steroid therapy has been well documented in infants. Successful antenatal treatment of a fetal hepatic hemangioma with maternal corticosteroids is reported. CASE: A 36-year-old woman, gravida 2, para 1, had an ultrasound at 17 weeks which showed a fetal hepatic hemangioma. Because of increase of the tumor and enlarged fetal heart, maternal oral corticosteroid therapy was commenced at 28 weeks, which progressively decreased the mass. The infant was delivered at 36 weeks with no evidence of heart failure, and at 7 months the tumor was barely seen on ultrasound. CONCLUSION: When an enlarging fetal hepatic hemangioma is detected antenatally, maternal corticosteroid therapy should be considered.
J Morris; J Abbott; P Burrows; D Levine
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  94     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1999 Nov 
Date Detail:
Created Date:  1999-12-07     Completed Date:  1999-12-07     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  813-5     Citation Subset:  AIM; IM    
Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
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MeSH Terms
Dexamethasone / therapeutic use*
Fetal Diseases / drug therapy*,  ultrasonography*
Glucocorticoids / therapeutic use*
Hemangioma / drug therapy*,  ultrasonography*
Liver Neoplasms / drug therapy*,  ultrasonography*
Prenatal Care
Ultrasonography, Prenatal*
Reg. No./Substance:
0/Glucocorticoids; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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