Document Detail


Antenatal dexamethasone and renal vascular resistance in preterm infants.
MedLine Citation:
PMID:  17444834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare vascular resistance, renal volume and insulin levels in preterm infants with and without antenatal steroids. METHODS: We studied 61 preterm infants (37 with (group A) and 24 without antecedent of antenatal steroids (group B)). We measured insulin levels at birth in cord blood samples. Ultrasound measurements to evaluate renal arteries resistance index and renal volume were performed during the first 72 h of birth. RESULTS: Preterm infants from group A tended to have lower weight and gestational age than those from group B. Resistance index in renal arteries was lower in preterm infants with steroid therapy compared with group B (right renal artery 0.73 vs. 0.80; P=0.001, and left renal artery 0.75 vs. 0.79; P=0.01, respectively). Renal volume and insulin levels were not different between the groups. In the multiple regression analysis for factors associated with resistance index of renal arteries, only antenatal steroids use was included in the model (R2=0.13; P=0.003 and R2=0.10; P=0.01 for left and right renal arteries, respectively). CONCLUSION: Antenatal dexamethasone in preterm infants during the first 72 h of birth seems to decrease resistance index in renal arteries without affecting renal volume and insulin levels.
Authors:
Norma Amador-Licona; Juan Manuel Guízar-Mendoza; Jesús Alejandro Maciel-Miranda; Gustavo Romero-Gutiérrez
Related Documents :
17513934 - Is there a role for tocolytic therapy during conservative management of preterm prematu...
14671874 - The impact of multiple preterm births on the family.
17065584 - Anti-annexin a2 igm antibody in preterm infants: its association with chorioamnionitis.
17148004 - The impact of multiple gestations on late preterm (near-term) births.
12537224 - Outcome at 2 years of infants with congenital diaphragmatic hernia: a population-based ...
6864374 - Use of nerve conduction velocity to determine gestational age in infants at risk and in...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  43     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-20     Completed Date:  2007-07-19     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  303-6     Citation Subset:  IM    
Affiliation:
Unidad de Investigación Epidemiológica, UMAE 48 Bajío, Mexico.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Dexamethasone / pharmacology,  therapeutic use*
Female
Glucocorticoids / pharmacology,  therapeutic use*
Humans
Infant, Newborn
Infant, Premature*
Insulin / analysis
Kidney / blood supply*
Male
Mexico
Prenatal Care
Renal Artery / physiopathology*,  ultrasonography
Vascular Resistance / drug effects*
Chemical
Reg. No./Substance:
0/Glucocorticoids; 11061-68-0/Insulin; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prediction of severe hyperbilirubinaemia using the Bilicheck transcutaneous bilirubinometer.
Next Document:  Bony lesions in BCG-vaccinated children: consider BCG osteitis.