Document Detail

Antenatal corticosteroids--current thinking.
MedLine Citation:
PMID:  12763117     Owner:  NLM     Status:  MEDLINE    
Numerous investigations have indicated that antenatal corticosteroid administration reduces neonatal morbidity in preterm infants. Despite this, antenatal corticosteroid usage continued to be low on both sides of the Atlantic up to the late 1980s and early 1990s. Antenatal corticosteroid therapy finally came of age in 1995 with the publication of the National Institutes of Health Consensus Statement on effects of corticosteroids for fetal maturation on perinatal outcomes. The randomised trials of antenatal corticosteroid therapy have been based on the use of dexamethasone or betamethasone. However, observational evidence indicates differences in outcome, which may relate to the preparations themselves or to the preservatives included.
Patricia Crowley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  110 Suppl 20     ISSN:  1470-0328     ISO Abbreviation:  BJOG     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-05-23     Completed Date:  2003-07-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  77-8     Citation Subset:  AIM; IM    
Trinity College Dublin, Coombe Women's Hospital, Dublin, Ireland.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use*
Betamethasone / administration & dosage
Dexamethasone / administration & dosage
Gestational Age
Glucocorticoids / administration & dosage
Infant, Newborn
Infant, Premature, Diseases / prevention & control*
Pregnancy Outcome
Prenatal Care / methods*
Randomized Controlled Trials as Topic
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Glucocorticoids; 378-44-9/Betamethasone; 50-02-2/Dexamethasone

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