| Antenatal corticosteroids--current thinking. | |
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MedLine Citation:
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PMID: 12763117 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Numerous investigations have indicated that antenatal corticosteroid administration reduces neonatal morbidity in preterm infants. Despite this, antenatal corticosteroid usage continued to be low on both sides of the Atlantic up to the late 1980s and early 1990s. Antenatal corticosteroid therapy finally came of age in 1995 with the publication of the National Institutes of Health Consensus Statement on effects of corticosteroids for fetal maturation on perinatal outcomes. The randomised trials of antenatal corticosteroid therapy have been based on the use of dexamethasone or betamethasone. However, observational evidence indicates differences in outcome, which may relate to the preparations themselves or to the preservatives included. |
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Authors:
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Patricia Crowley |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 110 Suppl 20 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2003 Apr |
Date Detail:
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Created Date: 2003-05-23 Completed Date: 2003-07-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 77-8 Citation Subset: AIM; IM |
Affiliation:
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Trinity College Dublin, Coombe Women's Hospital, Dublin, Ireland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use* Betamethasone / administration & dosage Dexamethasone / administration & dosage Female Gestational Age Glucocorticoids / administration & dosage Humans Infant, Newborn Infant, Premature, Diseases / prevention & control* Pregnancy Pregnancy Outcome Prenatal Care / methods* Randomized Controlled Trials as Topic |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Glucocorticoids; 378-44-9/Betamethasone; 50-02-2/Dexamethasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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