Document Detail

Antenatal corticosteroids after preterm premature rupture of membranes.
MedLine Citation:
PMID:  21508704     Owner:  NLM     Status:  In-Data-Review    
Preterm premature rupture of membranes (PPROM) is an obstetrical complication associated with high neonatal morbidity and mortality. The current management of PPROM focuses on neonatal benefit and includes the ancillary use of corticosteroids for fetal maturation. The purpose of this work was to provide a comprehensive and unbiased review of the available literature on prenatal administration of corticosteroids in conditions of PPROM, and to address the rationale and the relevant supporting evidence for this practice. We conclude that the cumulative level I evidence indicates a definite beneficial effect of corticosteroids in conditions of PPROM.
Alex C Vidaeff; Susan M Ramin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  54     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-04-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  337-43     Citation Subset:  IM    
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, Houston, Texas.
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