| Antecedents of schizophrenia and affective illness. Obstetric complications. | |
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MedLine Citation:
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PMID: 7663821 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: This exploratory study seeks to generate new hypotheses about the relationship between obstetric complications and schizophrenia. METHOD: The British Perinatal Mortality Survey represents 98% of all births during one week in March 1958 in Great Britain. Present State Examination (PSE), Catego diagnoses of narrowly defined schizophrenia (n = 49), broadly defined schizophrenia (n = 79), affective psychosis (n = 44) and neurosis (n = 93) were derived from case notes for all cohort members. The remainder of the cohort, surviving the perinatal period, acted as controls (n = 16 812). Variables in the British Perinatal Mortality Survey were grouped into five categories: the physique/lifestyle of the mother (including demographic characteristics), her obstetric history, the current pregnancy, the delivery and the condition of the baby. RESULTS: There were 7/17 significant differences in maternal physique/lifestyle and obstetric history between the births of schizophrenics and controls, compared to 4/40 comparisons of somatic variables relating to pregnancy, birth and the condition of the baby. This compares with 4/17 and 7/40 for affective psychotics and a total of 4/57 differences for all categories of variables when neurotics were contrasted with controls. CONCLUSIONS: The purported increased risk of obstetric complications in schizophrenics may result from the physique/lifestyle of their mothers. |
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Authors:
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A Sacker; D J Done; T J Crow; J Golding |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The British journal of psychiatry : the journal of mental science Volume: 166 ISSN: 0007-1250 ISO Abbreviation: Br J Psychiatry Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-10-10 Completed Date: 1995-10-10 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 0342367 Medline TA: Br J Psychiatry Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 734-41 Citation Subset: IM |
Affiliation:
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Psychology Division, University of Hertfordshire, Hatfield, Herts. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Affective Disorders, Psychotic
/
diagnosis,
psychology* Brain Damage, Chronic / diagnosis, psychology* Child of Impaired Parents / psychology Cohort Studies Delirium, Dementia, Amnestic, Cognitive Disorders / diagnosis, psychology Female Great Britain Humans Infant, Newborn Life Style Male Neurotic Disorders / diagnosis, psychology Obstetric Labor Complications / diagnosis, psychology* Pregnancy Prenatal Exposure Delayed Effects Risk Factors Schizophrenia / diagnosis* Schizophrenic Psychology* |
| Comments/Corrections | |
Comment In:
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Br J Psychiatry. 1995 Nov;167(5):694-5; author reply 696-7
[PMID:
8564335
]
Br J Psychiatry. 1995 Nov;167(5):695-6; author reply 696-7 [PMID: 8564336 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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