| Antecedent hypertension interacts with adverse ventricular remodeling after myocardial infarction. | |
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MedLine Citation:
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PMID: 15819299 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Ventricular remodeling is an independent predictor of left ventricular function in patients with myocardial infarction (MI). Accelerated ventricular remodeling is a probable contributor to the increased mortality observed after MI in hypertensive patients. The purpose of this study is to assess the relationship of antecedent hypertension to ventricular remodeling after MI. METHODS: Seventy-nine patients presenting with a first acute MI (AMI) who were treated and attained Thrombolysis In Myocardial Infarction (TIMI) flow grade 3 with re-perfusion therapy within 12 hours of their symptom onset were enrolled in this study. All of them underwent left ventriculography (LVG) immediately after re-perfusion therapy and again at 6 months after the occurrence of MI. Patients were divided into two groups; hypertensive group and normotensive group. End-diastolic volume index (EDVI), end-systolic volume index (ESVI), and EF were compared between acute phase and 6 months after AMI in each group. RESULTS: The hypertensive group showed a significant increase in both EDVI and ESVI after 6 months, whereas the normotensive group did not. In addition, there was no change in EF in the hypertensive group, whereas EF increased significantly after 6 months in the normotensive group. As a result, percent change in ESVI and EF showed significantly differences between the hypertensive group and normotensive group, whereas percent change in EDVI showed no significant difference between the two groups. CONCLUSIONS: Antecedent hypertension interacts with ventricular remodeling after MI. |
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Authors:
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Kimio Kamimori; Minoru Yoshiyama; Yoshihisa Shimada; Hidetaka Iida; Yasuhiro Nakamura; Eiji Uchida; Ken Yoshida; Satoshi Jissho; Shota Fukuda; Kazuhide Takeuchi; Junichi Yoshikawa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Osaka city medical journal Volume: 50 ISSN: 0030-6096 ISO Abbreviation: Osaka City Med J Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2005-04-11 Completed Date: 2005-04-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376413 Medline TA: Osaka City Med J Country: Japan |
Other Details:
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Languages: eng Pagination: 53-9 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Japan. m5059985@msic.med.osaka-cu.ac.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Case-Control Studies Female Humans Hypertension / complications* Male Middle Aged Myocardial Infarction / complications*, physiopathology* Stroke Volume Ventricular Remodeling* |
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