| Antacid-induced osteomalacia. | |
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MedLine Citation:
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PMID: 8929782 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case of a 49-year-old woman suffering from generalized skeletal pain and multiple fractures accompanied by severe hypophosphataemia and low urinary phosphorus excretion is reported. She had been taking large amounts of antacids containing aluminum hydroxide for many years. A diagnosis of antacid-induced osteomalacia was made. It was confirmed by biological work-up, radiographs and bone biopsy. A dramatic biological, osteodensitometric, and clinical improvement was achieved by withdrawal of antacids and phosphorus administration. The literature concerning this unusual condition has been reviewed. |
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Authors:
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Y Boutsen; J P Devogelaer; J Malghem; H Noel; C Nagant de Deuxchaisnes |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical rheumatology Volume: 15 ISSN: 0770-3198 ISO Abbreviation: Clin. Rheumatol. Publication Date: 1996 Jan |
Date Detail:
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Created Date: 1997-04-02 Completed Date: 1997-04-02 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8211469 Medline TA: Clin Rheumatol Country: BELGIUM |
Other Details:
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Languages: eng Pagination: 75-80 Citation Subset: IM |
Affiliation:
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Department of Rheumatology, St-Luc University Hospital, Louvain University in Brussels, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antacids / adverse effects*, therapeutic use Biopsy, Needle Bone Density Female Heartburn / drug therapy Humans Hypophosphatemia / chemically induced* Male Middle Aged Osteomalacia / chemically induced*, diagnosis, physiopathology, therapy Phosphorus / administration & dosage, therapeutic use Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Antacids; 7723-14-0/Phosphorus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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