Document Detail


Anorectic effect of ephedrine.
MedLine Citation:
PMID:  3653677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Different doses of ephedrine (3.1-50 mg kg-1) were given intraperitoneally to rats and found to decrease food intake dose-dependently. 2. The anorectic effect of ephedrine was decreased by animal pretreatment with pimozide, but phenoxybenzamine, propranolol and methergoline did not decrease the response. 3. The results show that the anorexia produced by ephedrine may be due to indirect dopaminergic mechanism of the drug.
Authors:
M R Zarrindast; T Hosseini-Nia; F Farnoodi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  General pharmacology     Volume:  18     ISSN:  0306-3623     ISO Abbreviation:  Gen. Pharmacol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-11-20     Completed Date:  1987-11-20     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7602417     Medline TA:  Gen Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  559-61     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Faculty of Medicine, University of Tehran, Iran.
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MeSH Terms
Descriptor/Qualifier:
Animals
Appetite Depressants* / antagonists & inhibitors
Ephedrine / antagonists & inhibitors,  pharmacology*
Feeding Behavior / drug effects
Metergoline / pharmacology
Pimozide / pharmacology
Rats
Sympatholytics / pharmacology
Chemical
Reg. No./Substance:
0/Appetite Depressants; 0/Sympatholytics; 17692-51-2/Metergoline; 2062-78-4/Pimozide; 299-42-3/Ephedrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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