| Anorectal physiologic testing for bowel dysfunction in patients with spinal cord lesions. | |
| | |
MedLine Citation:
|
PMID: 10910237 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: Bowel dysfunction is common in patients with spinal cord lesions. This study aims to determine whether there are any discriminatory findings at anorectal physiologic testing in patients with spinal cord lesions. METHODS: Twelve consecutive patients (6 females) with significant spinal cord lesions who had mixed symptoms of constipation, fecal impaction, and fecal incontinence were evaluated by perfusion manometry and pudendal nerve terminal motor latency. None of the patients had a sphincter defect as evaluated by endoanal ultrasonography. RESULTS: The median age was 54 (range, 40-87) years. Eight (67 percent) of them had had traumatic spinal cord injuries. Other spinal cord lesions included spina bifida, syringomyelia, arachnoid cyst, and spinal cord ischemia after abdominal aortic aneurysm repair. In patients with spinal cord lesions, the mean (range) resting anal canal pressure and maximum squeeze anal canal pressure were 46 (10-100) mmHg and 76 (30-120) mmHg respectively compared with 62 (50-70) mmHg, and 138 (100-180) mmHg, respectively, in healthy controls. Eleven (92 percent) patients had prolonged pudendal nerve terminal motor latency (9 bilateral and 2 unilateral) whereas rectoanal inhibitory reflex was abolished in all 9 patients tested. CONCLUSIONS: Spinal patients with severe bowel symptoms tended to have lower anal canal pressures than healthy controls. Pudendal netropathy and impaired rectoanal inhibitory reflex are common and may be important in the pathogenesis of bowel dysfunction in patients with spinal cord lesions. |
| | |
Authors:
|
J J Tjandra; B S Ooi; W R Han |
Related Documents
:
|
15845217 - Clinical and histological features of multiple meningiomas compared with solitary menin... 14756477 - Spinal epidural abscesses: conservative treatment for selected subgroups of patients. 10728207 - Radiofrequency lesions of the dorsal root ganglion in the treatment of hip flexor spasm... 6828807 - Frequency and spectrum of pulmonary diseases in patients with chronic renal failure ass... 18706027 - Homocysteine and stroke prevention: have the trials settled the issue? 23625177 - Intrathecal soluble hla-e correlates with disease activity in patients with multiple sc... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Diseases of the colon and rectum Volume: 43 ISSN: 0012-3706 ISO Abbreviation: Dis. Colon Rectum Publication Date: 2000 Jul |
Date Detail:
|
Created Date: 2000-08-02 Completed Date: 2000-08-02 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0372764 Medline TA: Dis Colon Rectum Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 927-31 Citation Subset: IM |
Affiliation:
|
Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Victoria, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Constipation / etiology, physiopathology* Fecal Incontinence / etiology, physiopathology* Humans Manometry Middle Aged Spinal Cord Injuries / complications* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Strictureplasty in Crohn's disease: surgical option.
Next Document: Postoperative colonic motility and tone in patients after colorectal surgery.