| Anorectal manometry with water-perfused catheter in healthy adults with no functional bowel disorders. | |
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MedLine Citation:
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PMID: 19210672 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Anorectal manometry provides an objective assessment of anal sphincter pressure and rectal sensitivity and anorectal reflexes in response to distension. However, its clinical utility is hampered by a lack of standardized protocols and normative data from healthy subjects. Previous studies have used water-perfused systems in normal subjects, but some adopted a rapid pull-through technique; others did not evaluate rectal sensations and others did not carefully exclude patients with functional bowel disorders. Objective To evaluate anorectal function in healthy adults without functional bowel disorders, using a water-perfused system with the stationary technique in order to obtain normative values for anorectal manometry. Method Fifty-two healthy volunteers with no Rome II diagnostic criteria for functional bowel disorders, including only nulliparous women, underwent anorectal manometry with a water-perfused system, according to a standardized protocol. Results Maximum squeeze pressure of the anal sphincter as well as the area under the pressure-time curve during squeeze was significantly lower in women than men (P < 0.01), while sphincter length, resting pressure, volume thresholds for reflex inhibitory recto-anal and rectal sensations were similar. Conclusions This study describes a protocol for stationary anorectal manometry using a water-perfused system, and a method for analysing the various parameters obtained during the procedure, as recently suggested in the international literature. It supplies normative data obtained in a population of healthy subjects including nulliparous women, with no functional bowel disorders. |
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Authors:
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Publication Detail:
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Type: Journal Article Date: 2009-02-06 |
Journal Detail:
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Title: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland Volume: 12 ISSN: 1463-1318 ISO Abbreviation: Colorectal Dis Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-05-07 Completed Date: 2010-09-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883611 Medline TA: Colorectal Dis Country: England |
Other Details:
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Languages: eng Pagination: 220-5 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anal Canal / physiology* Female Humans Male Manometry / methods* Middle Aged Pressure Rectum / physiology* Reference Values |
| Investigator | |
Investigator/Affiliation:
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Maura Corsetti / ; Sandro Passaretti / ; Franco Barzaghi / ; Eugenio Limido / ; Corrado Bottini / ; Gaetano Tessera / ; Luigi Gianfrate / ; Sara Bonecco / ; Roberto Antonio Noris / ; Valeriano Castagna / ; Franco Radaelli / ; Enrico Strocchi / ; Marco Dinelli / ; Daniela Fossati / ; Elena Strada / ; Giovanni Viviani / ; Domenico Della Casa / ; Guido Missale / |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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