| Anorectal manometry in patients with chronic constipation: a single-center experience. | |
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MedLine Citation:
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PMID: 18613380 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: Constipation is a common complaint, but its clinical presentation varies with each individual. The aim of this study was to evaluate anorectal physiology in a prospective group of patients with chronic constipation. METHODOLOGY: A total of 24 consecutive patients with constipation underwent solid-state anorectal manometry. Fifteen healthy controls were also studied. The anorectal parameters included resting and squeeze sphincter pressure, sensory thresholds in response to balloon distension, compliance of rectum, and rectoanal inhibitory reflex (RAIR). RESULTS: The rectal sensitivity for urge and pain did not differ between the groups, but the threshold volume for first sensation was higher in patients with constipation (p < 0.05). There was no group difference in the volume threshold for RAIR. However, the prevalence of impaired RAIR was higher in constipated patients. Anal pressure was lower in patients for maximal squeeze (p < 0.05). There was a positive correlation between the anal sphincter length and resting pressure in patients (r = 0.51, p = 0.03) and healthy controls (r = 0.72, p = 0.01). CONCLUSIONS: Constipated patients are characterized by impaired rectal sensitivity and decreased anal sphincter contractile pressure. Anorectal manometry is helpful for diagnosing anorectal dysfunction in patients with chronic constipation. |
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Authors:
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Tso-Tsai Liu; Chien-Lin Chen; Chih-Hsun Yi |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 55 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2008 Mar-Apr |
Date Detail:
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Created Date: 2008-07-10 Completed Date: 2008-12-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 426-9 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology and Hepatology, Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Anal Canal / physiopathology* Chronic Disease Constipation / physiopathology* Female Humans Male Manometry / methods Middle Aged Prospective Studies Rectum / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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