Document Detail


Anorectal complications and function in patients suffering from inflammatory bowel disease: a series of patients with long-term follow-up.
MedLine Citation:
PMID:  24965857     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIM: The aim of this study is to describe the long-term course of anorectal complains and function in a single centre cohort patients suffering from inflammatory bowel disease (IBD) with perianal lesions.
METHODS: Between 1993 and 2000, 56 IBD patients (43 Crohn's disease and 13 ulcerative colitis) with perianal complaints underwent anorectal function evaluation (AFE) (baseline). For follow-up, they were approached between 2010 and 2012 by sending questionnaires including Inflammatory Bowel Disease Quality of Life Questionnaire (IBDQ), Perianal Disease Activity Index (PDAI), faecal incontinence scale (Vaizey) and an invitation for AFE.
RESULTS: At follow-up, 46 patients (82 %) were available, 9 (16 %) were lost and 1 (2 %) had died. Thirty patients returned the questionnaires of which 17 also underwent AFE. The remaining 16 patients were interviewed by phone and were only willing to mention their anorectal complaints. Median follow-up was 14 year. In 25 of the 46 patients (54 %), perianal complaints persisted faecal incontinence (n = 7); soiling (n = 13) and active fistula (n = 5). Eighteen (39 %) patients had an active fistula at baseline and three persisted at follow-up. Two developed a new fistula. Mean IBDQ, Vaizey and PDAI were 178 (SD 29), 7 (SD 5) and 4.2 (SD 3.0), respectively. In 17 patients, who underwent AFE, anal endosonography showed healing in nine of the ten fistulas. Anal pressures as well as rectal capacity remained unaltered in the individual patient, but showed a large range within the group.
CONCLUSION: After 14 years, 54 % of the IBD patients with perianal lesions still have mild complaints. The quality of life remained moderate over a long period, which is concerning.
Authors:
Tze J Lam; Adriaan A van Bodegraven; Richelle J F Felt-Bersma
Related Documents :
24529487 - Early electrodiagnostic abnormalities in acute inflammatory demyelinating polyneuropath...
23868567 - Phrenic nerve stimulation in crt patients and benefits of electronic lead repositioning...
24075897 - Decreased resting-state interhemispheric coordination in first-episode, drug-naive para...
23133067 - Acute gallstone pancreatitis: a constant challenge for the surgeon.
23729807 - Dcr3 mutations in patients with juvenile-onset systemic lupus erythematosus lead to enh...
24153897 - Clinical characteristics of scleroderma patients with and without pulmonary hypertension.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-26
Journal Detail:
Title:  International journal of colorectal disease     Volume:  -     ISSN:  1432-1262     ISO Abbreviation:  Int J Colorectal Dis     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607899     Medline TA:  Int J Colorectal Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Differential effects of water-based exercise on the cognitive function in independent elderly adults...
Next Document:  Comparison of serial debulking and cytoreductive surgery with hyperthermic intraperitoneal chemother...