Document Detail

Anomalous serum thyroxin measurements with the Abbott TDx procedure.
MedLine Citation:
PMID:  2119915     Owner:  NLM     Status:  MEDLINE    
We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.
S Levine; R Noth; A Loo; I J Chopra; G G Klee
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  36     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-11-21     Completed Date:  1990-11-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1838-40     Citation Subset:  IM    
Clinical Laboratory, VA Medical Center, Martinez, CA 94553.
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MeSH Terms
Antibodies / analysis
Diagnostic Errors
False Negative Reactions
Hypothyroidism / blood
Thyroxine / blood*,  immunology,  standards
Thyroxine-Binding Proteins / analysis
Reg. No./Substance:
0/Antibodies; 0/Thyroxine-Binding Proteins; 7488-70-2/Thyroxine
Comment In:
Clin Chem. 1994 Oct;40(10):1976-7   [PMID:  7923783 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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