Document Detail

Anomalous origin of the main stem of the left coronary artery from the pulmonary trunk presenting with left ventricular hypertrophy.
MedLine Citation:
PMID:  17244377     Owner:  NLM     Status:  MEDLINE    
Patients with anomalous origin of the left coronary artery from the pulmonary trunk may present with paroxysmal angina on exertion, congestive heart failure, dyspnoea, syncope or sudden death. The association of such anomalous origin of the left coronary artery from the pulmonary trunk with a hypertrophic left ventricle is extremely rare. In our cohort of patients with anomalous origin of the left coronary artery from the pulmonary trunk, two presented with a hypertrophic left ventricle. We discuss these cases, accompanied by a review of the English literature describing different morphological anomalies of the coronary arteries associated with left ventricular hypertrophy. Whether the hypertrophy is a result of the evolvement of the collateral coronary system, or due to an additional pathological gene for hypertrophic obstructive cardiomyopathy, remains an enigma. The hypertrophy may have served as a compensatory mechanism accounting for the atypical clinical presentation. We further discuss the possible factors associating the occurrence of anomalous origin of the left coronary artery from the pulmonary trunk and myohypertrophy, supported by the documentation of the regression of hypertrophy following surgical correction of the anomalous arterial origin as seen in our patients.
Liat Gelernter-Yaniv; Avraham Lorber
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Cardiology in the young     Volume:  17     ISSN:  1047-9511     ISO Abbreviation:  Cardiol Young     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-07     Completed Date:  2007-05-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  78-83     Citation Subset:  IM    
Pediatric Cardiology Unit, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel.
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MeSH Terms
Combined Modality Therapy
Coronary Vessel Anomalies / diagnosis*,  therapy*
Diagnosis, Differential
Echocardiography, Doppler
Hypertrophy, Left Ventricular / diagnosis*,  therapy*
Pulmonary Artery / abnormalities*

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