Document Detail

Anomalous origin of the left coronary artery from the pulmonary artery: a case series and brief review.
MedLine Citation:
PMID:  18377554     Owner:  NLM     Status:  MEDLINE    
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiovascular defect that occurs in approximately 1/300 000 live births or 0.5% of children with congenital heart disease. The mortality of untreated ALCAPA has been estimated to range from 35% to greater than 85% in the first year of life. However, in some cases patients can survive past infancy and into adulthood and do not present with symptoms until later in life. These older patients often manifest their anomalies as congestive heart failure, malignant arrhythmias, or even sudden death. We report a series of 3 cases from our institution illustrating the various late presentations of this unusual diagnosis. We review the pathophysiology of this rare congenital anomaly and discuss some of the signs, symptoms, and diagnostic tests that can help diagnose this unusual condition in adults.
Andrew C Lee; Elyse Foster; Yerem Yeghiazarians
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Congenital heart disease     Volume:  1     ISSN:  1747-0803     ISO Abbreviation:  -     Publication Date:  2006 May 
Date Detail:
Created Date:  2008-04-01     Completed Date:  2008-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101256510     Medline TA:  Congenit Heart Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-5     Citation Subset:  IM    
Division of Cardiology, University of California, San Francisco, CA 94143, USA.
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MeSH Terms
Arterio-Arterial Fistula / diagnosis*,  physiopathology,  surgery
Cardiac Surgical Procedures
Coronary Vessel Anomalies / diagnosis*,  physiopathology,  surgery
Heart Catheterization
Middle Aged
Pregnancy Complications, Cardiovascular / diagnosis*,  physiopathology
Pulmonary Artery / abnormalities*

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