Document Detail


Anomalies of chromosome 1 as a possible prognostic index in childhood acute lymphoblastic leukemia.
MedLine Citation:
PMID:  3855688     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Complete remission rates, remission duration, and survival were established in children with acute lymphoblastic leukemia (ALL) with chromosome #1 anomalies, and the results were compared with those in patients with normal karyotypes or other chromosomal changes. Even though the complete remission rate did not differ significantly among the three groups, remission duration and survival were significantly longer in children ALL and chromosome #1 anomalies as compared with those in the other two groups.
Authors:
J R Kowalczyk; A A Sandberg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  15     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-04-11     Completed Date:  1985-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  303-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Chromosome Aberrations / genetics,  pathology
Chromosome Disorders
Chromosomes, Human, 1-3*
Female
Humans
Karyotyping
Leukemia, Lymphoid / genetics*
Male
Prognosis
Grant Support
ID/Acronym/Agency:
N01-CO-65341/CO/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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