| Ano-perianal tuberculosis: 15 years of clinical experiences in Southern Taiwan. | |
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MedLine Citation:
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PMID: 19832872 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Ano-perianal tuberculosis (TB) is a rare extrapulmonary form of the disease. Most publications are in case report form. We report our cohort retrospective study on ano-perianal TB, which is one of the very few original reports in the literature. METHOD: Over a period of 15 years (January 1992-December 2006), file records revealed cases with confirmed diagnosis of ano-perianal TB after screening from a total of 1251 patients with the diagnosis of TB from Chang Gung Memorial Hospital-Kaohsiung, Taiwan. RESULTS: This study recruited 17 patients (14 male patients and 3 female patients). The age ranged from 18 to 81 years with a mean age of 44.8 +/- 18.2 years. Thirteen patients had coexistent pulmonary TB (76.5%). Eight patients had at least one concomitant co-morbid illness (47.1%). The most common clinical manifestations were anal fistulae (n = 16). All patients who completed a full course of anti-mycobacterial treatment for at least 6 months after surgical intervention were cured without recurrence except for one patient who was lost to follow-up after 2 months of treatment. Seven of the nine patients with complicated fistulae needed longer anti-mycobacterium treatment duration (9-18 months). CONCLUSION: Ano-perianal TB should be kept in mind for all patients with prolonged or repeatedly recurrent ano-perianal symptoms and signs such as complicated fistulae in an endemic TB area like Taiwan. Management strategy is with conventional anti-mycobacterium therapy for at least 6 months after surgery. An extension of the anti-mycobacterium treatment course to 9-18 months is mandatory for patients with complicated disease presentations. |
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Authors:
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W-C Tai; T-H Hu; C-H Lee; H-H Chen; C-C Huang; S-K Chuah |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2009-10-13 |
Journal Detail:
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Title: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland Volume: 12 ISSN: 1463-1318 ISO Abbreviation: Colorectal Dis Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-29 Completed Date: 2010-11-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883611 Medline TA: Colorectal Dis Country: England |
Other Details:
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Languages: eng Pagination: e114-20 Citation Subset: IM |
Affiliation:
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Division of Hepato-Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Anal Canal / microbiology*, pathology Anus Diseases / diagnosis, epidemiology*, microbiology Diagnosis, Differential Female Follow-Up Studies Humans Incidence Male Middle Aged Mycobacterium tuberculosis / isolation & purification* Retrospective Studies Taiwan / epidemiology Time Factors Tuberculosis, Gastrointestinal / diagnosis, epidemiology*, microbiology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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