| Annular vesiculobullous eruptions in type 2 reaction in borderline lepromatous leprosy: a case report. | |
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MedLine Citation:
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PMID: 20704077 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An untreated case of BL presented with clinical features of type 2 reaction (T2R) confirmed by histopathology. The case was a 18-year-old female with borderline lepromatous leprosy who developed annular vesiculobullous eruptions oversome of the pre-existing plaques on arms and upper back along with fever and severe neuritis after a short course of ofloxacin intake prescribed for urinary tract infection. In addition to the above lesions, some of the existing lesions showed acute exacerbation characterized by erythema, oedema, tenderness and vesiculobullous eruption. This can be considered as an example of leprous exacerbation as described in older literature. T2Rs are common in lepromatous leprosy and not so uncommonly are observed in borderline lepromatous leprosy. The vesiculobullous and crusted lesions developing over the existing borderline plaques, some of them presenting in an annular pattern in T2R in the form of leprous exacerbation, have been reported rarely in the literature. |
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Authors:
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H K Kar; A Raina; P K Sharma; M Bhardwaj |
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3740017 - Human cannibalism: a case report. 1783787 - The factors influencing the operational efficiency of leprosy case detection programme. |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Indian journal of leprosy Volume: 81 ISSN: 0254-9395 ISO Abbreviation: Indian J Lepr Publication Date: 2009 Oct-Dec |
Date Detail:
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Created Date: 2010-08-13 Completed Date: 2010-09-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8409173 Medline TA: Indian J Lepr Country: India |
Other Details:
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Languages: eng Pagination: 205-8 Citation Subset: IM |
Affiliation:
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Department of Dermatology, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi-110001, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Clofazimine / administration & dosage Dose-Response Relationship, Drug Drug Therapy, Combination Erythema Nodosum / drug therapy, pathology* Female Glucocorticoids / administration & dosage Humans Leprostatic Agents / administration & dosage Leprosy, Borderline / complications, drug therapy, pathology* Leprosy, Lepromatous / drug therapy, pathology* Prednisolone / administration & dosage Recurrence Skin / pathology Skin Diseases, Vesiculobullous / complications, drug therapy, pathology* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 0/Leprostatic Agents; 2030-63-9/Clofazimine; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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