| Annular geometry and motion in human ischemic mitral regurgitation: novel assessment with three-dimensional echocardiography and computer reconstruction. | |
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MedLine Citation:
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PMID: 15561036 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Annular geometry and motion in functional ischemic mitral regurgitation are incompletely understood. Three-dimensional echocardiography demonstrates saddle-shaped annular geometry, but standard methodology does not enable quantification of annular motion. Therefore, a novel technique using three-dimensional echocardiography and computer software was used to characterize alterations in mitral annular geometry and motion in patients with ischemic mitral regurgitation. METHODS: We developed a computer program to reconstruct the mitral annulus based on spatial coordinates from three-dimensional echocardiography. Data were obtained at end-diastole and end-systole in 7 patients with ischemic mitral regurgitation and 5 normal control subjects. Mitral annular motion was quantified by calculating the displacement area of the annulus between end-diastole and end-systole. RESULTS: Comparison of ischemic mitral regurgitation and control patients revealed differences in annular geometry and motion at end-diastole. Annular perimeter was greater in ischemic mitral regurgitation patients (10.7 +/- 0.7 cm versus 8.6 +/- 0.2 cm in control group; p < 0.03), with increased intertrigonal distance in ischemic mitral regurgitation patients (2.8 +/- 0.3 cm versus 2.1 +/- 0.1 cm; p < 0.06). These changes resulted in increased annular orifice area in ischemic mitral regurgitation patients (9.1 +/- 1.2 cm2 versus 5.7 +/- 0.3 cm2; p < 0.03). Ischemic mitral regurgitation patients had altered annular motion, with reduced movement of the posterior annulus (5.4 +/- 0.7 cm2 versus 8.7 +/- 1.1 cm2; p < 0.03). CONCLUSIONS: Computer analysis of data obtained from three-dimensional echocardiography demonstrates altered annular geometry and motion in patients with ischemic mitral regurgitation. Patients with ischemic mitral regurgitation have annular dilatation, with an increase in anterior and posterior annular perimeters; this is accompanied by an increase in the intertrigonal distance and restriction of annular motion. |
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Authors:
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Rashid M Ahmad; A Marc Gillinov; Patrick M McCarthy; Eugene H Blackstone; Carolyn Apperson-Hansen; Jian Xin Qin; Deborah Agler; Takahiro Shiota; Delos M Cosgrove |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 78 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2004-11-24 Completed Date: 2005-07-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 2063-8; discussion 2068 Citation Subset: AIM; IM |
Affiliation:
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Department of Thoracic and Cardiovascular Surgery. The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Case-Control Studies Echocardiography, Three-Dimensional* Humans Image Processing, Computer-Assisted* Middle Aged Mitral Valve / anatomy & histology*, physiology*, ultrasonography Mitral Valve Insufficiency / pathology*, physiopathology*, ultrasonography Motion Prospective Studies Software |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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