Document Detail


Annular geometry and motion in human ischemic mitral regurgitation: novel assessment with three-dimensional echocardiography and computer reconstruction.
MedLine Citation:
PMID:  15561036     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Annular geometry and motion in functional ischemic mitral regurgitation are incompletely understood. Three-dimensional echocardiography demonstrates saddle-shaped annular geometry, but standard methodology does not enable quantification of annular motion. Therefore, a novel technique using three-dimensional echocardiography and computer software was used to characterize alterations in mitral annular geometry and motion in patients with ischemic mitral regurgitation. METHODS: We developed a computer program to reconstruct the mitral annulus based on spatial coordinates from three-dimensional echocardiography. Data were obtained at end-diastole and end-systole in 7 patients with ischemic mitral regurgitation and 5 normal control subjects. Mitral annular motion was quantified by calculating the displacement area of the annulus between end-diastole and end-systole. RESULTS: Comparison of ischemic mitral regurgitation and control patients revealed differences in annular geometry and motion at end-diastole. Annular perimeter was greater in ischemic mitral regurgitation patients (10.7 +/- 0.7 cm versus 8.6 +/- 0.2 cm in control group; p < 0.03), with increased intertrigonal distance in ischemic mitral regurgitation patients (2.8 +/- 0.3 cm versus 2.1 +/- 0.1 cm; p < 0.06). These changes resulted in increased annular orifice area in ischemic mitral regurgitation patients (9.1 +/- 1.2 cm2 versus 5.7 +/- 0.3 cm2; p < 0.03). Ischemic mitral regurgitation patients had altered annular motion, with reduced movement of the posterior annulus (5.4 +/- 0.7 cm2 versus 8.7 +/- 1.1 cm2; p < 0.03). CONCLUSIONS: Computer analysis of data obtained from three-dimensional echocardiography demonstrates altered annular geometry and motion in patients with ischemic mitral regurgitation. Patients with ischemic mitral regurgitation have annular dilatation, with an increase in anterior and posterior annular perimeters; this is accompanied by an increase in the intertrigonal distance and restriction of annular motion.
Authors:
Rashid M Ahmad; A Marc Gillinov; Patrick M McCarthy; Eugene H Blackstone; Carolyn Apperson-Hansen; Jian Xin Qin; Deborah Agler; Takahiro Shiota; Delos M Cosgrove
Related Documents :
8204236 - False negative transesophageal echocardiography in a patient with severe mitral regurgi...
11053696 - Prognostic significance of mild mitral regurgitation by color doppler echocardiography ...
9861576 - Cardiac side-effects of two selective serotonin reuptake inhibitors in middle-aged and ...
3278656 - Valvular heart disease: clinical approach to acute decompensation of left-sided lesions.
300216 - Aortic stenosis, angina pectoris, and coronary artery disease.
15262826 - Fish intake and risk of incident atrial fibrillation.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  78     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-11-24     Completed Date:  2005-07-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2063-8; discussion 2068     Citation Subset:  AIM; IM    
Affiliation:
Department of Thoracic and Cardiovascular Surgery. The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Case-Control Studies
Echocardiography, Three-Dimensional*
Humans
Image Processing, Computer-Assisted*
Middle Aged
Mitral Valve / anatomy & histology*,  physiology*,  ultrasonography
Mitral Valve Insufficiency / pathology*,  physiopathology*,  ultrasonography
Motion
Prospective Studies
Software

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hemodynamic changes during posterior vessel off-pump coronary artery bypass: comparison between deep...
Next Document:  Tricuspid valve repair: an old disease, a modern experience.