Document Detail

Annular gap junctions in cuboidal ependymocytes of the median eminence of the rat after intraventricular administration of methysergide and thyrotropin releasing hormone.
MedLine Citation:
PMID:  3135112     Owner:  NLM     Status:  MEDLINE    
The annular gap junctions in the cuboidal ependymocytes of the median eminence of rats were studied after intraventricular administration (3rd ventricle) of methysergide and thyrotropin releasing hormone. Isolated annular gap junctions were found in the ependymocytes of normal animals. In experimental rats an increase was observed in the number of annular gap junctions at 5 min after administration of the drugs; the increase was more apparent at 10 min postadministration. Likewise, the ependymocytes showed a clear development of the Golgi complex and an increase in the number of vesicles close to the lateral membranes. Accordingly, the increase observed in annular gap junctions could be interpreted as a sign of cellular activity indicative of a greater exchange of substances through the ependymocytes.
R Vàzquez; J F Carvajal; E Pèrez; J Carretero; J M Riesco; E Blanco
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of submicroscopic cytology and pathology     Volume:  20     ISSN:  1122-9497     ISO Abbreviation:  J. Submicrosc. Cytol. Pathol.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-08-31     Completed Date:  1988-08-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8804312     Medline TA:  J Submicrosc Cytol Pathol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  297-304     Citation Subset:  IM    
Department of Morphological Sciences, University of Salamanca, Spain.
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MeSH Terms
Ependyma / cytology*,  physiology,  ultrastructure
Injections, Intraventricular
Intercellular Junctions / physiology,  ultrastructure*
Median Eminence / cytology*,  physiology,  ultrastructure
Methysergide / administration & dosage,  pharmacology*
Rats, Inbred Strains
Thyrotropin-Releasing Hormone / administration & dosage,  pharmacology*
Reg. No./Substance:
24305-27-9/Thyrotropin-Releasing Hormone; 361-37-5/Methysergide

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