Document Detail

Annular elastolytic giant cell granuloma in an infant: improvement after treatment with oral tranilast and topical pimecrolimus.
MedLine Citation:
PMID:  16227100     Owner:  NLM     Status:  MEDLINE    
Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-old boy that was successfully treated with oral tranilast and topical pimecrolimus (Elidel 1.0% cream).
Hae-Woong Lee; Mi-Woo Lee; Jee-Ho Choi; Kee-Chan Moon; Jai-Kyoung Koh
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  53     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-17     Completed Date:  2006-05-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S244-6     Citation Subset:  IM    
Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
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MeSH Terms
Administration, Oral
Administration, Topical
Anthranilic Acids / administration & dosage,  therapeutic use*
Anti-Allergic Agents / administration & dosage,  therapeutic use*
Elastic Tissue / pathology*
Granuloma Annulare / drug therapy*,  pathology
Immunosuppressive Agents / administration & dosage,  therapeutic use*
Tacrolimus / administration & dosage,  analogs & derivatives*,  therapeutic use
Reg. No./Substance:
0/Anthranilic Acids; 0/Anti-Allergic Agents; 0/Immunosuppressive Agents; 0/pimecrolimus; 109581-93-3/Tacrolimus; 53902-12-8/tranilast

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