| Ankylosing spondylitis in women. | |
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MedLine Citation:
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PMID: 6245628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although ankylosing spondylitis (AS) has been considered rare in women, we believe that its incidence is underestimated. In our case studies of 12 women with AS the characteristic clinical features of the disease included onset before the age of 30 (12 patients); night pain and morning stiffness (12 patients); intermittent, migratory joint pain (9 patients); and history of uveitis (2 patients). Spine mobility was decreased in all patients. Sacroiliac (SI) (8 patients) and circumthoracic (5 patients) tenderness were common findings. If these pertinent clues are present, further diagnostic studies are indicated. Histocompatibility testing for the HLA-B27 antigen, which is reported to be present in over 90% of patients with AS, is useful in detecting early and mild forms of the disease. We found the antigen in 10 of 11 patients tested. Radioisotope (RI) scanning can show early inflammation of the SI joints long before changes are evident on standard roentgenograms: In 3 cases, SI films were reported as normal but RI scans revealed abnormal uptake and ratios. Early detection of AS prevents inappropriate treatment of patients and mislabeling them as functional complainers. |
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Authors:
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C E Goodman; R K Lange; J Waxman; T E Weiss |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of physical medicine and rehabilitation Volume: 61 ISSN: 0003-9993 ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 1980 Apr |
Date Detail:
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Created Date: 1980-06-16 Completed Date: 1980-06-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 167-70 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Diphosphates / diagnostic use Female HLA Antigens / analysis Humans Middle Aged Sacroiliac Joint / radionuclide imaging Sex Factors Spondylitis, Ankylosing / diagnosis*, immunology, radionuclide imaging Technetium / diagnostic use Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Diphosphates; 0/HLA Antigens; 7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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