Document Detail

Ankle peak systolic velocity: new parameter to predict nonhealing in diabetic foot lesions.
MedLine Citation:
PMID:  19769805     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to determine whether ankle peak systolic velocity (APSV) can predict nonhealing in diabetic foot lesions. Diabetic patients referred for duplex scanning of the lower extremity arteries were included if they had foot lesions such as ulcers, gangrene, or tissue necrosis and had no palpable pedal pulses. End points were healed or healing foot lesions, revascularization, major amputation, or death. One hundred consecutive limbs were included. Forty-three limbs with diabetic foot lesions reached the end point of adequate healing or complete healing, whereas 57 limbs had nonhealing lesions. The APSV was significantly higher in limbs with healed or healing lesions compared with limbs with nonhealed lesions: 53.0 cm/s (41.8-81.6) versus 19.2 cm/s (12.4-26.5), p < .0001. At a cutoff point of 35 cm/s, the APSV showed a sensitivity of 92.9% (95% confidence interval [CI] 82-97), a specificity of 90.6% (95% CI 76-96), a positive predictive value of 92.9%, and a negative predictive value of 90.6% in predicting nonhealing of diabetic foot lesions. There was a significant difference between the APSV before and after revascularization: 20.4 cm/s (12.4-26.3) versus 48.8 cm/s (36.1-80.8), p < .0001. APSV could predict nonhealing of diabetic foot lesions with a high degree of accuracy in this group of patients.
Rashad A Bishara; Wassila Taha; Ihab Akladious; Muhammad A Allam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vascular     Volume:  17     ISSN:  1708-5381     ISO Abbreviation:  Vascular     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-09-22     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101196722     Medline TA:  Vascular     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  264-8     Citation Subset:  IM    
Department of Vascular Surgery, ElSahel Teaching Hospital, Shoubra, Cairo, Egypt.
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MeSH Terms
Ankle / blood supply*,  ultrasonography
Blood Flow Velocity / physiology
Diabetic Foot / physiopathology*,  surgery
Ischemia / physiopathology,  ultrasonography
Middle Aged
Predictive Value of Tests
Prospective Studies
Risk Factors
Systole / physiology
Treatment Outcome
Ultrasonography, Doppler, Duplex
Wound Healing / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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