| Anitschkow nuclear changes in postmortem pericardial scrapings. | |
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MedLine Citation:
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PMID: 11284306 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To document the presence of Anitschkow nuclear changes (ANC) in pericardial mesothelium at autopsy after the incidental finding of ANC in pericardial scrapings from a fatal case of overwhelming sepsis. STUDY DESIGN: Fourteen, nonconsecutive autopsy cases were studied. Using the edge of a scalpel, the visceral pericardium from the left ventricle was scraped, and the sample was smeared onto glass slides, fixed in 95% ethanol, Papanicolaou stained and evaluated for the presence of ANC. Histologic correlation was also performed. RESULTS: ANC were observed in pericardial mesothelial cells in 6 of 14 cases. Sepsis was the cause of death in three. Fatal cardiac arrhythmia, T-cell lymphoma and fulminant hepatic necrosis were found in the remaining cases. While readily seen in cytologic preparations, ANC were found focally in only one case examined histologically. CONCLUSION: Postmortem cytologic evaluation provides information relevant to the autopsy. In this study, ANC were very clearly seen in six pericardial scrapings. Clinical correlation supports the current theory that ANC represent a nonspecific reactive cell change. |
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Authors:
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C P Molina; V J Schnadig |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cytologica Volume: 45 ISSN: 0001-5547 ISO Abbreviation: Acta Cytol. Publication Date: 2001 Mar-Apr |
Date Detail:
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Created Date: 2001-04-03 Completed Date: 2001-04-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370307 Medline TA: Acta Cytol Country: United States |
Other Details:
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Languages: eng Pagination: 197-200 Citation Subset: IM |
Affiliation:
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Division of Cytopathology, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0548, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Autopsy Cell Nucleus / ultrastructure* Cytodiagnosis Epithelium / ultrastructure Humans Male Middle Aged Pericardium / ultrastructure* |
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