Document Detail

Anisakidosis: report of 25 cases and review of the literature.
MedLine Citation:
PMID:  7621671     Owner:  NLM     Status:  MEDLINE    
Anisakidosis (previously known as anisakiasis) is a disease caused by the accidental ingestion of larval nematodes (Anisakis and sometimes Pseudoterranova) in raw fish. Two groups of patients are studied: 5 clinical cases and 20 serological diagnoses. 55 French cases are already published. Most of them complained of acute symptoms, which occurred within 12 h of eating the seafood meal--epigastric pain, occlusion, diffuse abdominal pain, and appendicitis. Larvae were attached to the gastric mucosa (25 cases), including an inflammatory response (erythema, oedema ulceration). Diagnosis of anisakiasis is made by gastroscopy which allows removal of the worms, and cures the patients. In gastro-intestinal tract X-rays, oedema in the mucosa, pseudo tumour formation, and filling defects (worm) were observed. In chronic infections, cases with intermittent feelings of ill health and abdominal pain, lasting from several weeks to months, were misdiagnosed as another intestinal disease. Positive serological reactions are helpful, and surgery is necessary for resection of the lesion; diagnosis is made histologically by an eosinophilic granuloma, and the presence of a larva with Y shaped lateral cords. Infestation rate is high in fishes: cod (88%), rock fish (86%), herring (88%), salmon, mackerel. Public health education should discourage the eating of raw fish. Thorough cooking to 70 degrees C or adequate freezing to -20 degrees C for 72 h are the best preventive measures. Such legislation is only in force in the Netherlands, where cases have decreased dramatically.
P Bouree; A Paugam; J C Petithory
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Comparative immunology, microbiology and infectious diseases     Volume:  18     ISSN:  0147-9571     ISO Abbreviation:  Comp. Immunol. Microbiol. Infect. Dis.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-08-31     Completed Date:  1995-08-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7808924     Medline TA:  Comp Immunol Microbiol Infect Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  75-84     Citation Subset:  IM    
Department of Parasitology, Bicetre Hospital, Paris-XI University, Kremlin-Bicetre, France.
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MeSH Terms
Abdominal Pain / etiology
Acute Disease
Anisakiasis / diagnosis,  epidemiology,  etiology*,  therapy
Anisakis / drug effects,  immunology,  isolation & purification*
Antibodies, Helminth / analysis
Chronic Disease
Fishes / parasitology
Food Parasitology
France / epidemiology
Gastric Mucosa / parasitology*
Middle Aged
Reg. No./Substance:
0/Antibodies, Helminth

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