Document Detail


Anion binding induced conformational changes exploited for recognition, sensing and pseudorotaxane disassembly.
MedLine Citation:
PMID:  23014946     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Investigations to exploit the anion binding induced conformational changes displayed by a new class of acyclic receptor for anion recognition, fluorescence sensing and pseudorotaxane disassembly are described. A series of imidazolium-appended bis-amide-pyridine, pyridine N-oxide and pyridinium containing receptors are synthesised and their anion binding properties elucidated using (1)H NMR spectroscopy. Upon anion recognition, the receptors exhibit a substantial conformational change from an 'open' to a more 'closed' intramolecular geometry. The fluorescence anion sensing ability of a bis-pyrene-functionalised analogue is investigated, with anion-induced responses arising from excimer signalling mechanisms. A pseudorotaxane assembly formed between the pyridine N-oxide receptor acting as a threading component and an isophthalamide macrocycle is demonstrated to undergo disassembly resulting from the conformational behaviour exhibited by the thread upon chloride binding.
Authors:
Graeme T Spence; Carmen Chan; Fridrich Szemes; Paul D Beer
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-27
Journal Detail:
Title:  Dalton transactions (Cambridge, England : 2003)     Volume:  -     ISSN:  1477-9234     ISO Abbreviation:  Dalton Trans     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101176026     Medline TA:  Dalton Trans     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK. paul.beer@chem.ox.ac.uk.
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