Document Detail


Animal models for autoimmune bullous dermatoses.
MedLine Citation:
PMID:  19702839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Autoimmune bullous dermatoses are a group of severe diseases, which are clinically characterized by blisters and erosions of skin and/or mucous membranes. In order to investigate the pathogenesis of these potentially life-threatening diseases and to develop more specific therapeutic approaches, animal models have been developed that aim to reproduce the clinical, histological and immunopathological findings. We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations.
Authors:
Katja Bieber; Shijie Sun; Norito Ishii; Michael Kasperkiewicz; Enno Schmidt; Misa Hirose; J?rgen Westermann; Xinhua Yu; Detlef Zillikens; Ralf J Ludwig
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-08-21
Journal Detail:
Title:  Experimental dermatology     Volume:  19     ISSN:  1600-0625     ISO Abbreviation:  Exp. Dermatol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-04-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301549     Medline TA:  Exp Dermatol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  2-11     Citation Subset:  IM    
Affiliation:
Institute of Anatomy, University of L?beck, L?beck, Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Autoimmune Diseases*
Disease Models, Animal*
Immunization, Passive*
Skin Diseases, Vesiculobullous*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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