Document Detail

Animal experiments on an absorbable synthetic thread made of polyglycolic acid (PGA) in corneal surgery.
MedLine Citation:
PMID:  1098429     Owner:  NLM     Status:  MEDLINE    
Monofilaments of the absorbable synthetic thread Dexon made from PGA have properties similar to nylon 10-0. Experiments with intra-lamellar implantation of the monofilament in rabbit corneas showed the same good material tolerance as nylon 10-0. Perforating corneal wounds were closed with interrupted and running sutures from PGA monofilaments, respectively. One week post-operatively, increased intraocular pressure caused a wound rupture but not a thread rupture. Two weeks post-operatively an increased intraocular pressure of more than 300 mm Hg could no longer rupture the wound. Slit lamp and histological examinations revealed symptoms of absorption after the second week. According to our findings, PGA monofilaments may be suitable for corneal surgery in patients.
J Faulborn; P Leu; G Mackensen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Advances in ophthalmology = Fortschritte der Augenheilkunde = Progrès en ophtalmologie     Volume:  30     ISSN:  0065-3004     ISO Abbreviation:  Adv Ophthalmol     Publication Date:  1975  
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0263212     Medline TA:  Adv Ophthalmol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  43-50     Citation Subset:  IM    
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MeSH Terms
Cornea / pathology,  surgery*
Evaluation Studies as Topic
Foreign-Body Reaction / pathology
Intraocular Pressure
Polyglycolic Acid* / adverse effects
Stress, Mechanical
Suture Techniques
Sutures* / adverse effects*
Reg. No./Substance:
0/Nylons; 26009-03-0/Polyglycolic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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