Document Detail


Anhydro sugar and linkage contributions to circular dichroism of agarose and carrageenan, with conformational implications.
MedLine Citation:
PMID:  9345754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The geometry-dependent linkage contributions to the circular dichroism (CD) of agarose and carrageenan were determined by subtracting the monomeric CD from the CD of the polymers. For this purpose, the CD of methyl 3,6-anhydro-alpha-D-galactopyranoside, and of other anhydro sugars, was measured. Application of empirical quadrant rules indicates the observed CD to be that expected for the helical conformations of agarose and carrageenan as derived from diffraction data and modeling calculations. The difference in CD sign in the two polymers arises from a translocation of the beta-D-galactose O-2 atom from one quadrant to the neighboring quadrant of the C-5-O-5-C-1 ether chromophore of the preceding anhydro sugar residue, demonstrating the unusually high spatial resolution of conformational analysis that can be achieved with CD under favorable circumstances.
Authors:
E R Arndt; E S Stevens
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Carbohydrate research     Volume:  303     ISSN:  0008-6215     ISO Abbreviation:  Carbohydr. Res.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1998-02-04     Completed Date:  1998-02-04     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0043535     Medline TA:  Carbohydr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  73-8     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Binghamton University, NY 13902-6016, USA.
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MeSH Terms
Descriptor/Qualifier:
Carbohydrate Conformation
Carbohydrate Sequence
Carbohydrates / chemistry*
Carrageenan / chemistry*
Circadian Rhythm / physiology*
Molecular Sequence Data
Sepharose / chemistry*
Grant Support
ID/Acronym/Agency:
46465//PHS HHS
Chemical
Reg. No./Substance:
0/Carbohydrates; 9000-07-1/Carrageenan; 9012-36-6/Sepharose

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