| Anglo-Saxon pharmacopoeia revisited: a potential treasure in drug discovery. | |
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MedLine Citation:
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PMID: 21782968 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Three of the four major Anglo-Saxon collections reporting medicinal formulations in England from the 10th century, the Old English Herbarium, Bald's Leechbook and the Lacnunga, could contain leads and insights into new medicinal uses. Previous pharmacological studies of medicinal plants mentioned in Anglo-Saxon medical texts, suggested that some were effective and led to the identification and isolation of natural compounds. For example, matricin from yarrow Achillea millefolium L., is a proprionic acid analogue that yields chamazulene carboxylic acid with cyclooxygenase-2 activity similar to that of ibuprofen. As we discuss here, multidisciplinary projects could further explore historical texts to discover additional plant metabolites with potential pharmacological applications. |
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Authors:
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Frances Watkins; Barbara Pendry; Olivia Corcoran; Alberto Sanchez-Medina |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-18 |
Journal Detail:
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Title: Drug discovery today Volume: - ISSN: 1878-5832 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9604391 Medline TA: Drug Discov Today Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Medicines Research Group, School of Health and Bioscience, University of East London, Romford Road, London E15 4LZ, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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