Document Detail

Angiotensin-converting enzyme inhibitors--when to use?
MedLine Citation:
PMID:  3069209     Owner:  NLM     Status:  MEDLINE    
Heart failure is difficult to define and quantify, and this makes it difficult to assess the relative value of different drug regimens. Although there are theoretical reasons suggesting that ACE inhibitors might be useful in all patients with heart failure, there are cogent arguments to the contrary. In practice, angiotensin-converting enzyme inhibitors have been shown to given considerable relief to patients with severe heart failure, but in patients who are only moderately ill these drugs may have less effect than increasing the dose of diuretics. Vasodilators in general probably reduce the fatality of patients with heart failure, but the effect is not specific to angiotensin-converting enzyme inhibitors.
J R Hampton; A J Cowley
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology     Volume:  75 Suppl 1     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1988  
Date Detail:
Created Date:  1989-04-27     Completed Date:  1989-04-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  118-25     Citation Subset:  IM    
Queen's Medical Centre, University Hospital, Nottingham, UK.
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MeSH Terms
Angiotensin-Converting Enzyme Inhibitors / adverse effects,  therapeutic use*
Heart Failure / drug therapy*
Hemodynamics / drug effects
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors

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