Document Detail


Angiotensin converting enzyme in the serum of rats with experimental silicosis.
MedLine Citation:
PMID:  6309208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The development of silicosis in rats given an intratracheal dose of silica was followed both by normal histological procedures and by measuring the level of angiotensin converting enzyme in the serum. The histological changes demonstrated a variable response due to the uneven deposition of material given by the intratracheal route. While the enzyme activity in the serum increased in the treated group it was not well correlated with the histological changes.
Authors:
R C Brown; D E Munday; V M Sawicka; J C Wagner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of experimental pathology     Volume:  64     ISSN:  0007-1021     ISO Abbreviation:  Br J Exp Pathol     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-10-08     Completed Date:  1983-10-08     Revised Date:  2012-05-07    
Medline Journal Info:
Nlm Unique ID:  0372543     Medline TA:  Br J Exp Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  286-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Ferric Compounds
Lung / pathology
Male
Peptidyl-Dipeptidase A / blood*
Rats
Rats, Inbred Strains
Silicon Dioxide
Silicosis / enzymology*,  pathology
Titanium
Chemical
Reg. No./Substance:
0/Ferric Compounds; 1309-37-1/ferric oxide; 13463-67-7/titanium dioxide; 7440-32-6/Titanium; 7631-86-9/Silicon Dioxide; EC 3.4.15.1/Peptidyl-Dipeptidase A
Comments/Corrections

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