| Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study. | |
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MedLine Citation:
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PMID: 9509698 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The angioplasty substudy of the GUSTO IIb trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (MI). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who underwent primary angioplasty either died or suffered a disabling stroke or another myocardial infarction within 30 days, compared with 13.7% of patients who received fibrinolytic therapy, for an odds ratio of 0.67 (P = .033). This difference was less than in previous studies, possibly in part because fibrinolytic therapy has improved. The findings underscore the importance of promptly restoring complete, brisk, antegrade flow in the infarct-related artery, regardless of what treatment is used. |
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Authors:
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S J Brener |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Cleveland Clinic journal of medicine Volume: 65 ISSN: 0891-1150 ISO Abbreviation: Cleve Clin J Med Publication Date: 1998 Feb |
Date Detail:
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Created Date: 1998-04-22 Completed Date: 1998-04-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8703441 Medline TA: Cleve Clin J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 75-81 Citation Subset: IM |
Affiliation:
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Department of Interventional Cardiology, Cleveland Clinic Foundation, OH 44195, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty* Fibrinolytic Agents / therapeutic use* Humans Myocardial Infarction / drug therapy*, mortality, surgery* Randomized Controlled Trials as Topic Survival Rate Thrombolytic Therapy* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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