Document Detail

Angiolymphoid hyperplasia with eosinophilia showing prominent granulomatous and fibrotic reaction: a morphological and immunohistochemical study.
MedLine Citation:
PMID:  17122496     Owner:  NLM     Status:  MEDLINE    
Angiolymphoid hyperplasia with eosinophilia is an uncommon condition that usually presents in early to middle-aged adults as multiple red nodules or plaques, most commonly on the head and neck. It can also occur on the trunk and limbs, and rarely at other sites such as the breast and oral mucosa. Although one-third of these lesions recur, surgical excision is curative. The histopathological hallmark is the presence of blood vessels with plump epithelioid endothelial cells. The nonvascular component consists of histiocytes, plasma cells, eosinophils, and lymphocytes. The occurrence of numerous giant cells in the stroma of angiolymphoid hyperplasia with eosinophilia is extremely unusual and such a finding in association with diffuse granulomatous/fibrous reaction has not been reported. We describe such a lesion that developed in the wrist of a 34-year-old pregnant female.
Ricardo S Macarenco; Abaetê Leite do Canto; Sergio Gonzalez
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  28     ISSN:  0193-1091     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-23     Completed Date:  2007-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  514-7     Citation Subset:  IM    
CIPAX-Surgical Pathology and Cytopathology Institute, Sao Jose dos Campos, Sao Paulo State-Brazil.
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MeSH Terms
Angiolymphoid Hyperplasia with Eosinophilia / metabolism,  pathology*
Antigens, CD / metabolism
Antigens, CD31 / metabolism
Antigens, CD34 / metabolism
Antigens, Differentiation, Myelomonocytic / metabolism
Factor VIII / metabolism
Pregnancy Complications / pathology*
Reg. No./Substance:
0/Antigens, CD; 0/Antigens, CD31; 0/Antigens, CD34; 0/Antigens, Differentiation, Myelomonocytic; 0/CD68 antigen, human; 9001-27-8/Factor VIII

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