Document Detail


Angiolipoma in sellar, suprasellar and parasellar region: report on two new cases and review of literature.
MedLine Citation:
PMID:  21545775     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Angiolipomas of CNS are very rare; more than 90% involve the spinal canal. There are only a few case reports documenting the tumor in the sellar/suprasellar region. We report 2 cases of angiolipoma involving sellar/suprasellar and right parasellar region in two female patients. On histopathology the lesion was composed of vascular component which was of cavernous type in one patient and of capillary caliber in the other with admixture of mature adipocytes. The MRI findings were distinctive as the lesion was predominantly iso-to-hypointense on T1W sequence, hyperintense on T2WI and FLAIR sequence. In addition, a few small hyperintense areas were noted on plain T1W images which may represent intralesional fat. One of the cases also showed lipid lactate peak on MR spectroscopy. To the best of our knowledge only 8 other cases of sellar, parasellar angiolipomas have been reported in indexed literature. MRI with fat suppression sequences should be routinely performed in lesions in such locations with hyperintense areas on T1WI as the incidence of intraoperative blood loss is very high. A preoperative suspicion of the diagnosis might help in reducing the patient morbidity.
Authors:
N Ghosal; S V Furtado; N A Saikiran; K Gupta; A S Hegde
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical neuropathology     Volume:  30     ISSN:  0722-5091     ISO Abbreviation:  Clin. Neuropathol.     Publication Date:    2011 May-Jun
Date Detail:
Created Date:  2011-05-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214420     Medline TA:  Clin Neuropathol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
Affiliation:
1Department of Pathology and Transfusion Medicine, 2Department of Neurosurgery and 3Department of Radiology, SSSIHMS, Bangalore, India.
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