Document Detail

Angiographic no-reflow and six-month mortality in elderly (>/= 75 years old) Asian patients undergoing primary percutaneous coronary intervention: A single center experience from 1998 to 2007.
MedLine Citation:
PMID:  20443652     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We sought to report the incidence of angiographic no-reflow and clinical outcomes of elderly patients who have undergone primary percutaneous coronary intervention at a tertiary institution in Singapore over a period of 10 years. METHODS: A total of 141 patients (60% male) aged 75 or above underwent primary PCI between 1998 and 2007. Their average age was 80+/-5 years. Cardiogenic shock complicating STEMI on presentation accounted for 15% of the patients. RESULTS: At baseline, 103 (73%) patients have impaired TIMI flow grade (TIMI 0-2), and 38 (27%) have normal flow (TIMI 3). At the end of the procedure, 44 (31.2%) patients had no-reflow phenomenon (TIMI 0-2), whereas 97 (68.8%) achieved normal antegrade flow. Post-procedure corrected TIMI frame count was analyzable in 66% (n=93) of the patients. Post-procedure corrected TIMI frame count was>28 in 37.6% (n=35) of patients. In-hospital, 30-day and six-month mortalities were 20.6, 25.5% and 27.7%, respectively. Multivariable analysis showed that age 80 or above, low systolic blood pressure and final TIMI 0-2 flow independently predicted six-month mortality. CONCLUSIONS: We found that one-third of the treated patients developed no-reflow phenomenon. Six-month mortality was 27.7%, most were cardiac deaths that occurred during index hospitalization.
Chi-Hang Lee; Bee-Choo Tai; Adrian F Low; Swee-Guan Teo; Yean-Teng Lim; Huay-Cheem Tan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acute cardiac care     Volume:  12     ISSN:  1748-295X     ISO Abbreviation:  Acute Card Care     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101276603     Medline TA:  Acute Card Care     Country:  England    
Other Details:
Languages:  eng     Pagination:  63-9     Citation Subset:  IM    
Department of Medicine, National University of Singapore, Singapore.
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MeSH Terms
Age Factors
Angioplasty, Transluminal, Percutaneous Coronary*
Asian Continental Ancestry Group*
Cohort Studies
Coronary Angiography
No-Reflow Phenomenon / epidemiology*,  radiography,  therapy*
Retrospective Studies
Survival Rate
Treatment Outcome

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