| Angiographic impact of the GuardWire system on inflated coronary segments after six months: does the distal protection balloon of the GuardWire Plus lead to restenosis? | |
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MedLine Citation:
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PMID: 20562078 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To investigate the consequences of inflating low-pressure balloon occlusion devices in native coronary arteries. METHODS AND RESULTS: One hundred eighteen segments of 118 patients who were enrolled in the ASPARAGUS study were analysed post-procedure and at six months by means of quantitative coronary angiography. ASPARAGUS was a randomised study to assess the efficacy of the PercuSurge GuardWire system in acute myocardial infarction. Patients were divided into two groups; protection group (group P, n=53) and control group (group C, n=65). Matched 15 mm segments were selected for quantitative coronary angiographies using anatomical landmarks post-procedure and at six months. There were 118 matched QCA analysis (Group P 53, Group C 65). Baseline characteristics were similar between groups. The mean minimal lumen diameter (MLD) post procedure was 1.94+/-0.57 mm in group P and 1.92+/-0.57 mm in group C. The MLD at six months was 1.98+/-0.54 mm in group P and 1.92+/-0.54 mm in group C. There was virtually no late loss in both group (P: -0.04+/-0.38 mm, C: 0.00+/-0.38 mm, p=0.561). CONCLUSIONS: The inflation of the low-pressure PercuSurge balloon in native coronary arteries was not associated with angiographic vascular response during the 6-month follow-up. This finding may suggest the safety of using similar technology such as the low-pressure balloon system in human native coronary arteries. |
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Authors:
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Hiroyuki Kyono; Ken Kozuma; Toshiya Muramatsu; Satoshi Suwa; Naoya Fujita; Shiho Koyama; Masahiko Saito; Takaaki Isshiki |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
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Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 6 ISSN: 1969-6213 ISO Abbreviation: EuroIntervention Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-21 Completed Date: 2010-12-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
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Languages: eng Pagination: 257-60 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Teikyo University Hospital, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Balloon Occlusion
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adverse effects*,
instrumentation* Coronary Angiography* Coronary Restenosis / etiology*, radiography* Coronary Stenosis / therapy Female Humans Male Middle Aged Prospective Studies Time Factors |
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