Document Detail


Angiographic features of 26 children with Takayasu's arteritis.
MedLine Citation:
PMID:  12709750     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Takayasu's arteritis (TA) is a chronic idiopathic inflammatory disease affecting primarily the aorta, its proximal branches and the pulmonary arteries. OBJECTIVES: To retrospectively review the angiograms of children with TA so as to describe the patterns of vascular involvement. PATIENTS AND METHODS: Twenty-six children with TA who differed from most other studies in that almost all of them presented with hypertension, reflecting the incidence of abdominal aortic and renal artery involvement. RESULTS: The most consistent finding was stenosis of the aorta. Marginal irregularity/undulation of the aorta was also a useful angiographic diagnostic feature in subtle disease. The incidence of aneurysms was high compared to other studies and both fusiform and saccular aneurysms were encountered. Percutaneous transluminal angioplasty (PTA) was successful in all eight patients in whom it was performed. MRI, CT angiography and US are discussed as less invasive imaging alternatives. TA is a significant cause of renovascular hypertension in children in South Africa where there is a high incidence of tuberculous infection. Knowledge of the angiographic features and pattern of aortic involvement is essential for diagnosis and initiation of early and appropriate treatment, including PTA.
Authors:
Mignon McCulloch; Savvas Andronikou; Elizabeth Goddard; Paul Sinclair; John Lawrenson; Simone Mandelstam; Steve J Beningfield; Alastair J J W Millar
Publication Detail:
Type:  Journal Article     Date:  2003-02-05
Journal Detail:
Title:  Pediatric radiology     Volume:  33     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-23     Completed Date:  2003-07-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  230-5     Citation Subset:  IM    
Affiliation:
Department of Paediatric Nephrology, Red Cross War Memorial Children's Hospital, School of Child and Adolescent Health, University of Cape Town, Klipfontein Road, Rondebosch 7700, Cape Town, South Africa. MCCULL@ich.uht.ac.za
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Angioplasty, Balloon
Aortography
Child
Child, Preschool
Female
Humans
Male
Retrospective Studies
Takayasu Arteritis / radiography*,  therapy

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