| Angiographic evaluation of culprit lesions in acute coronary syndrome: relation to the original site on previous coronary angiography. | |
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MedLine Citation:
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PMID: 9626904 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Culprit lesions in acute coronary syndrome [acute myocardial infarction (AMI) and unstable angina pectoris (UAP)] were examined angiographically in 222 patients who had previously undergone coronary angiography (CAG). The observation period lasted 5 years after primary CAG in medically treated patients (group M, 127 cases) and after final follow-up CAG in patients treated by percutaneous transluminal coronary angioplasty (PTCA) (group B, 95 cases). There were 33 AMIs, including 5 deaths (22/127, 17.3%, in group M vs 11/95, 11.6%, in group B; p<0.01) and 189 UAPs (105/127, 82.7%, in group M vs 84/95, 88.4%, in group B; NS). High-grade stenoses (>75%) were found in 76 (59.8%) patients in group M, of which 41 lesions (54%) resulted in acute coronary syndromes (ACSs). In group M, ACSs resulted from insignificant stenosis (< or =50%) in 67 (53%) patients and from significant stenosis (>50%) in 60 (47%) patients. In group B, ACSs resulted from insignificant stenosis in 78 (82%) patients and from significant stenosis in 17 (18%) patients. Out of 95 PTCA sites, high-grade restenosis occurred in 3 lesions and ACSs (2 AMI, 14 UAP) in 16 (16.8%). We conclude that ACSs are more likely to develop from insignificant lesions than from significant lesions. High-grade stenoses are prone to become occlusive lesions and PTCA reduces this potential risk. Most target sites of PTCA that escaped restenosis were stable in the long term. |
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Authors:
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T Saito; H Date; I Taniguchi; S Nakamura; H Oka; Y Mizuno; K Noda; S Yamashita; S Oshima; H Yasue |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Japanese circulation journal Volume: 62 ISSN: 0047-1828 ISO Abbreviation: Jpn. Circ. J. Publication Date: 1998 May |
Date Detail:
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Created Date: 1998-08-12 Completed Date: 1998-08-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7806868 Medline TA: Jpn Circ J Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 359-63 Citation Subset: IM |
Affiliation:
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Cardiovascular Division, Kumamoto Central Hospital, Kumamoto City, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angina, Unstable / physiopathology, radiography, therapy* Angioplasty, Transluminal, Percutaneous Coronary* Coronary Angiography* Coronary Disease / physiopathology Humans Male Middle Aged Myocardial Infarction / physiopathology, radiography, therapy* Severity of Illness Index |
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